PGx Vendor Evaluation Criteria
| Criterion | What to Look For |
|---|---|
| Clinical validity | Peer-reviewed studies supporting the test's clinical utility |
| Gene panel breadth | Coverage of high-impact drug-gene pairs relevant to your population |
| Clinical decision support | Quality of alerts and recommendations provided to prescribers |
| EHR integration | Ability to integrate results with major EHR systems |
| Member experience | Ease of testing process and result delivery to members |
| ROI evidence | Published ROI data from employer implementations |
Clinical Validity
Clinical validity — the scientific evidence that the test accurately predicts drug response — is the most important PGx vendor evaluation criterion. Require vendors to provide peer-reviewed studies demonstrating the clinical utility of their test. Be skeptical of vendors who rely only on proprietary data or case studies.
ROI Guarantees
Pro Tip
Require ROI guarantees from PGx vendors. A vendor who is confident in their program will guarantee a minimum ROI — typically 3:1 to 5:1 within 24 months. ROI guarantees should be backed by performance reporting that allows you to verify actual savings. Vendors who refuse ROI guarantees are not confident in their program.